KMID : 0829220160400040855
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Korean Journal of Oral and Maxillofacial Pathology 2016 Volume.40 No. 4 p.855 ~ p.859
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Follicular Lymphoid Hyperplasia of the Hard Palate
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Cha Hyung-Seok
Lyu Dong-Lei Lee Jun Yoon Jung-Hoon
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Abstract
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The follicular lymphoid hyperplasia is a very rare nonneoplastic lymphoproliferative disease in the oral mucosa. Clinically, it usually presents as asymptomatic, non-ulcerated, normal-colored, soft, sessile, unilateral and slow growing mass in the posterior hard palate. Therefore, soft-tissue mass of the hard palate can be a difficult diagnostic challenge for the clinician. Herein, we report a case of follicular lymphoid hyperplasia located in the left posterior hard palate. A 40-year-old male presented a soft, non-ulcerated, painless mass of 1.5 ¡¿ 1.0cm in size. Radiographically, it was no bony involvement. Histology revealed germinal center surrounding mantle zone of small lymphocytes. Immunohistochemistry showed CD3,CD20 were postive but Bcl-2 and cyclin D1 were negative. The patient underwent surgical excision and 3-year follow-up has not shown any evidence of recurrence.
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KEYWORD
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Follicular lymphoid hyperplasia, lymphoma, hard palate, CD3, CD20
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