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KMID : 0829220160400040855
Korean Journal of Oral and Maxillofacial Pathology
2016 Volume.40 No. 4 p.855 ~ p.859
Follicular Lymphoid Hyperplasia of the Hard Palate
Cha Hyung-Seok

Lyu Dong-Lei
Lee Jun
Yoon Jung-Hoon
Abstract
The follicular lymphoid hyperplasia is a very rare nonneoplastic lymphoproliferative disease in the oral mucosa. Clinically, it usually presents as asymptomatic, non-ulcerated, normal-colored, soft, sessile, unilateral and slow growing mass in the posterior hard palate. Therefore, soft-tissue mass of the hard palate can be a difficult diagnostic challenge for the clinician. Herein, we report a case of follicular lymphoid hyperplasia located in the left posterior hard palate. A 40-year-old male presented a soft, non-ulcerated, painless mass of 1.5 ¡¿ 1.0cm in size. Radiographically, it was no bony involvement. Histology revealed germinal center surrounding mantle zone of small lymphocytes. Immunohistochemistry showed CD3,CD20 were postive but Bcl-2 and cyclin D1 were negative. The patient underwent surgical excision and 3-year follow-up has not shown any evidence of recurrence.
KEYWORD
Follicular lymphoid hyperplasia, lymphoma, hard palate, CD3, CD20
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